|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:activatedBy
|
gptkb:MEK5
|
|
gptkbp:alternativeName
|
gptkb:ERK5
Big MAP kinase 1
BMK1
|
|
gptkbp:discoveredBy
|
1995
|
|
gptkbp:encodedBy
|
MAPK7 gene
|
|
gptkbp:Entrez_Gene_ID
|
5598
ENSG00000166484
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
brain
heart
|
|
gptkbp:fullName
|
Mitogen-activated protein kinase 7
|
|
gptkbp:function
|
signal transduction
protein serine/threonine kinase activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0000165
GO:0004672
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:6882
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPK7
|
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:MEF2C
gptkb:SRC
gptkb:CHIP
gptkb:PML
gptkb:CREB1
gptkb:MEF2A
gptkb:MEF2D
gptkb:MEK5
|
|
gptkbp:involvedIn
|
gptkb:MAPK_signaling_pathway
cell differentiation
cell proliferation
cell survival
|
|
gptkbp:locatedOnChromosome
|
17p11.2
|
|
gptkbp:memberOf
|
gptkb:MAP_kinase_family
gptkb:ERK_subfamily
|
|
gptkbp:molecularWeight
|
~88 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:phosphorylates
|
gptkb:MEF2C
gptkb:MEF2A
gptkb:MEF2D
|
|
gptkbp:RefSeq
|
NM_139276
|
|
gptkbp:significance
|
implicated in cancer
implicated in cardiovascular disease
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q13164
|
|
gptkbp:bfsParent
|
gptkb:MEF2C
gptkb:ERK5_pathway
|
|
gptkbp:bfsLayer
|
7
|