MEF2A

GPTKB entity

Statements (52)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alternativeSplicing yes
gptkbp:associatedWith coronary artery disease
gptkbp:domain gptkb:MADS-box
gptkb:MEF2_domain
gptkbp:encodedBy MEF2A gene
gptkbp:Entrez_Gene_ID 4205
gptkbp:expressedIn gptkb:skeletal_muscle
brain
cardiac muscle
gptkbp:family MEF2 family
gptkbp:fullName Myocyte enhancer factor 2A
gptkbp:function transcription factor
gptkbp:HGNC_ID 6993
https://www.w3.org/2000/01/rdf-schema#label MEF2A
gptkbp:interactsWith gptkb:14-3-3_proteins
gptkb:HDAC4
gptkb:HDAC9
gptkbp:locatedOnChromosome gptkb:chromosome_15
gptkbp:mutationAssociatedWith familial coronary artery disease
gptkbp:OMIM 600660
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:mouse
gptkb:zebrafish
right
gptkbp:phosphorylates gptkb:p38_MAPK
gptkbp:postTranslationalModification phosphorylation
sumoylation
ubiquitination
acetylation
gptkbp:regulates gptkb:synaptic_plasticity
apoptosis
cell differentiation
gene expression
angiogenesis
immune response
cell cycle
neuronal differentiation
inflammatory response
muscle development
myogenesis
vascular development
cardiac hypertrophy
metabolic processes
cardiac gene expression
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:transcriptionalActivator yes
gptkbp:UniProtID Q02078
gptkbp:bfsParent gptkb:ERK5_pathway
gptkb:MEF2_proteins
gptkbp:bfsLayer 7