gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
gptkbp:alternativeSplicing
|
yes
|
gptkbp:associatedWith
|
coronary artery disease
|
gptkbp:domain
|
gptkb:MADS-box
gptkb:MEF2_domain
|
gptkbp:encodedBy
|
MEF2A gene
|
gptkbp:Entrez_Gene_ID
|
4205
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
cardiac muscle
|
gptkbp:family
|
MEF2 family
|
gptkbp:fullName
|
Myocyte enhancer factor 2A
|
gptkbp:function
|
transcription factor
|
gptkbp:HGNC_ID
|
6993
|
https://www.w3.org/2000/01/rdf-schema#label
|
MEF2A
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:HDAC4
gptkb:HDAC9
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_15
|
gptkbp:mutationAssociatedWith
|
familial coronary artery disease
|
gptkbp:OMIM
|
600660
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
gptkbp:phosphorylates
|
gptkb:p38_MAPK
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
ubiquitination
acetylation
|
gptkbp:regulates
|
gptkb:synaptic_plasticity
apoptosis
cell differentiation
gene expression
angiogenesis
immune response
cell cycle
neuronal differentiation
inflammatory response
muscle development
myogenesis
vascular development
cardiac hypertrophy
metabolic processes
cardiac gene expression
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
gptkbp:transcriptionalActivator
|
yes
|
gptkbp:UniProtID
|
Q02078
|
gptkbp:bfsParent
|
gptkb:ERK5_pathway
gptkb:MEF2_proteins
|
gptkbp:bfsLayer
|
7
|