|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
gptkb:MEK5
|
|
gptkbp:alsoKnownAs
|
gptkb:MAPK7
Big MAP kinase 1
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:encodedBy
|
MAPK7 gene
|
|
gptkbp:Entrez_Gene_ID
|
5598
ENSG00000166484
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
cell differentiation
cell proliferation
cell survival
signal transduction
regulation of gene expression
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ERK5
|
|
gptkbp:inhibitedBy
|
gptkb:XMD8-92
|
|
gptkbp:involvedIn
|
angiogenesis
cancer progression
cardiovascular development
|
|
gptkbp:locatedOnChromosome
|
chromosome 17q21.31
|
|
gptkbp:memberOf
|
gptkb:MAP_kinase_family
|
|
gptkbp:molecularWeight
|
~110 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
4IC7
|
|
gptkbp:phosphorylates
|
transcription factors
|
|
gptkbp:structure
|
contains kinase domain and C-terminal transcriptional activation domain
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q13164
|
|
gptkbp:bfsParent
|
gptkb:MAPK
gptkb:MAP_kinase_family
gptkb:ERK5_pathway
gptkb:MAPK_family
|
|
gptkbp:bfsLayer
|
7
|