|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:MEK5
MAPKK5
PRKMK5
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurological disorders
|
|
gptkbp:biologicalProcess
|
signal transduction
protein kinase activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodes
|
MEK5 protein
|
|
gptkbp:Entrez_Gene_ID
|
5607
ENSG00000115317
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
Mitogen-activated protein kinase kinase 5
|
|
gptkbp:function
|
dual specificity protein kinase
activates ERK5 (MAPK7)
|
|
gptkbp:gene
|
gptkb:MAP2K5
|
|
gptkbp:geneType
|
protein coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:6840
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAP2K5
|
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:MAP3K2
gptkb:MAP3K3
gptkb:MAPK7
|
|
gptkbp:involvedIn
|
gptkb:MAPK_signaling_pathway
cell proliferation
differentiation
stress response
|
|
gptkbp:locatedOnChromosome
|
15
15q23-q24
|
|
gptkbp:molecularWeight
|
44 kDa
|
|
gptkbp:numberOfExons
|
15
|
|
gptkbp:OMIM
|
602520
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:phosphorylates
|
gptkb:MAPK7
Ser311
Thr315
|
|
gptkbp:proteinFamily
|
gptkb:MAP_kinase_kinase_family
|
|
gptkbp:regulates
|
transcription factors
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q13163
|
|
gptkbp:bfsParent
|
gptkb:ERK5_pathway
gptkb:MAP_kinase_kinase_(MAP2K)
|
|
gptkbp:bfsLayer
|
7
|