|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:K-ras
gptkb:KRAS2
gptkb:RASK2
gptkb:c-K-ras
|
|
gptkbp:associatedWith
|
gptkb:cancer
colorectal cancer
pancreatic cancer
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:encodes
|
gptkb:KRAS_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000133703
3845
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:fullName
|
gptkb:Kirsten_rat_sarcoma_viral_oncogene_homolog
|
|
gptkbp:function
|
guanine nucleotide exchange factor
|
|
gptkbp:hasIsoform
|
gptkb:KRAS4A
gptkb:KRAS4B
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:6407
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Kras
|
|
gptkbp:involvedIn
|
gptkb:PI3K-AKT_signaling_pathway
gptkb:MAPK_signaling_pathway
|
|
gptkbp:locatedOn
|
gptkb:chromosome_12
|
|
gptkbp:memberOf
|
gptkb:RAS_gene_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:G12V
gptkb:G13D
G12D
|
|
gptkbp:OMIM
|
190070
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
cell survival
|
|
gptkbp:target
|
gptkb:adagrasib
gptkb:sotorasib
anticancer drugs
|
|
gptkbp:UniProtID
|
gptkb:P01116
|
|
gptkbp:bfsParent
|
gptkb:KRAS
|
|
gptkbp:bfsLayer
|
5
|