|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:C11orf43
gptkb:IGF-II
gptkb:somatomedin-A
multiplication-stimulating activity (MSA)
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:INS_gene
gptkb:Wilms_tumor
gptkb:H19_gene
gptkb:Beckwith-Wiedemann_syndrome
gptkb:Silver-Russell_syndrome
gptkb:IGF1_gene
|
|
gptkbp:biologicalProcess
|
embryonic development
cell growth
growth factor activity
metabolic process
|
|
gptkbp:cellularComponent
|
extracellular space
secreted
|
|
gptkbp:discoveredBy
|
Daughaday et al.
|
|
gptkbp:discoveredIn
|
1978
|
|
gptkbp:encodes
|
gptkb:insulin-like_growth_factor_II
|
|
gptkbp:Entrez_Gene_ID
|
3481
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:placenta
brain
liver
|
|
gptkbp:fullName
|
gptkb:insulin-like_growth_factor_2
|
|
gptkbp:function
|
cell differentiation
cell proliferation
fetal development
regulation of growth and development
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:5466
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IGF2 gene
|
|
gptkbp:imprint
|
yes
|
|
gptkbp:length
|
180 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
chromosome 11
|
|
gptkbp:mutationAssociatedWith
|
growth disorders
|
|
gptkbp:OMIM
|
147470
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Igf2
|
|
gptkbp:parentalExpression
|
paternal allele
|
|
gptkbp:proteinFamily
|
gptkb:insulin_superfamily
|
|
gptkbp:regulates
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
DNA methylation
insulin signaling pathway
CTCF binding
epigenetic imprinting
|
|
gptkbp:UniProtID
|
P01344
|
|
gptkbp:bfsParent
|
gptkb:IGF-II
gptkb:insulin-like_growth_factor_2
gptkb:insulin-like_growth_factor_II_protein
gptkb:ICR1
gptkb:Insulin-like_Growth_Factor
|
|
gptkbp:bfsLayer
|
7
|