|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Beckwith-Wiedemann_syndrome
gptkb:Silver-Russell_syndrome
|
|
gptkbp:biologicalProcess
|
cell proliferation
embryonic development
regulation of metabolism
growth factor activity
|
|
gptkbp:discoveredBy
|
Daughaday et al.
|
|
gptkbp:discoveredIn
|
1957
|
|
gptkbp:encodes
|
gptkb:IGF2_protein
|
|
gptkbp:Entrez_Gene_ID
|
3481
ENSG00000167244
|
|
gptkbp:expressedIn
|
paternal allele
|
|
gptkbp:fullName
|
gptkb:insulin-like_growth_factor_2
|
|
gptkbp:function
|
regulation of cell proliferation
fetal development
growth factor activity
|
|
gptkbp:HGNC_ID
|
5466
|
|
gptkbp:imprintingStatus
|
imprinted gene
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_11p15.5
|
|
gptkbp:mutationAssociatedWith
|
overgrowth syndromes
growth restriction
|
|
gptkbp:OMIM
|
147470
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Igf2
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
insulin signaling pathway
|
|
gptkbp:product
|
gptkb:insulin-like_growth_factor_II
|
|
gptkbp:recipient
|
gptkb:INSR
gptkb:IGF2R
gptkb:IGF1R
|
|
gptkbp:regulates
|
cell differentiation
cell growth
|
|
gptkbp:tissue_specificity
|
gptkb:placenta
fetal tissues
adult liver
|
|
gptkbp:UniProtID
|
P01344
|
|
gptkbp:bfsParent
|
gptkb:IGF2
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Igf2
|