insulin-like growth factor II

URI: https://gptkb.org/entity/insulin-like_growth_factor_II
GPTKB entity
Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation gptkb:IGF-II
gptkbp:associatedWith gptkb:Wilms_tumor
gptkb:cancer
gptkb:Beckwith-Wiedemann_syndrome
gptkb:Silver-Russell_syndrome
gptkbp:biologicalProcess embryonic development
regulation of apoptosis
regulation of cell growth
growth factor activity
cellular response to insulin stimulus
placental development
metabolic process
gptkbp:category growth factor
hormone
peptide
mitogen
gptkbp:discoveredBy 1957
gptkbp:Entrez_Gene_ID ENSG00000167244
gptkbp:foundIn humans
mammals
gptkbp:function cell differentiation
cell proliferation
regulation of growth and development
gptkbp:gene gptkb:IGF2
gptkbp:HGNC_ID HGNC:5466
https://www.w3.org/2000/01/rdf-schema#label insulin-like growth factor II
gptkbp:locatedOnChromosome gptkb:chromosome_11p15.5_(human)
gptkbp:molecularWeight 7.5 kDa
gptkbp:OMIM 147470
gptkbp:producedBy gptkb:placenta
liver
fetal tissues
gptkbp:recipient gptkb:insulin_receptor
gptkb:IGF2R
gptkb:IGF1R
gptkbp:RefSeq gptkb:NP_000609.1
gptkbp:regulates epigenetic regulation
imprinted gene
gptkbp:sequenceSimilarity gptkb:insulin
insulin-like growth factor I
gptkbp:structure single-chain polypeptide
gptkbp:UniProtID P01344
gptkbp:bfsParent gptkb:Igf2
gptkbp:bfsLayer 7