insulin-like growth factor II protein
GPTKB entity
Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:IGF-II
|
| gptkbp:binds |
gptkb:IGF1_receptor
gptkb:IGF2_receptor gptkb:insulin_receptor |
| gptkbp:discoveredIn |
1960s
|
| gptkbp:encodedBy |
gptkb:IGF2_gene
|
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
cell differentiation
cell proliferation regulation of growth and development |
| https://www.w3.org/2000/01/rdf-schema#label |
insulin-like growth factor II protein
|
| gptkbp:involves |
gptkb:cancer
gptkb:Beckwith-Wiedemann_syndrome gptkb:Silver-Russell_syndrome |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_11p15.5_(human)
|
| gptkbp:molecularWeight |
about 7.5 kDa
|
| gptkbp:presentIn |
adult circulation
fetal circulation |
| gptkbp:regulates |
imprinted gene expression
|
| gptkbp:relatedTo |
gptkb:insulin-like_growth_factor_I_protein
|
| gptkbp:role |
metabolic regulation
prenatal growth |
| gptkbp:secretes |
gptkb:placenta
liver other tissues |
| gptkbp:sequence |
similar to proinsulin
|
| gptkbp:structure |
polypeptide
|
| gptkbp:bfsParent |
gptkb:IGF2
|
| gptkbp:bfsLayer |
6
|