Statements (42)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:Wilms_tumor
|
| gptkbp:associated_with |
gptkb:Wilms_tumor
adrenal tumors hemihyperplasia macroglossia neonatal hypoglycemia omphalocele |
| gptkbp:caused_by |
overgrowth
|
| gptkbp:current_use |
gptkb:Peters_anomaly
gptkb:Cohen_syndrome gptkb:Silver-Russell_syndrome gptkb:Sotos_syndrome gptkb:Klinefelter_syndrome |
| gptkbp:descendant |
autosomal dominant
sporadic |
| gptkbp:first_described_by |
gptkb:1964
|
| gptkbp:future_plans |
variable prognosis
monitoring for tumors potential for normal development |
| gptkbp:genetic_diversity |
chromosomal abnormalities
imprinting defects |
| https://www.w3.org/2000/01/rdf-schema#label |
Beckwith-Wiedemann syndrome
|
| gptkbp:is_popular_in |
1 in 10,000 to 1 in 15,000 births
|
| gptkbp:named_after |
gptkb:J._Bruce_Beckwith
Hans Wiedemann |
| gptkbp:research_focus |
epigenetics
cancer predisposition genomic imprinting |
| gptkbp:risk_factor |
gptkb:physicist
family history advanced paternal age |
| gptkbp:social_responsibility |
genetic testing
clinical evaluation |
| gptkbp:symptoms |
developmental delays
kidney abnormalities facial asymmetry ear abnormalities large birth weight |
| gptkbp:treatment |
surgical intervention
hormonal therapy |