HRas proto-oncogene, GTPase

URI: https://gptkb.org/entity/HRas_proto-oncogene,_GTPase
GPTKB entity
Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alternativeName gptkb:c-Ha-ras
gptkb:HRAS
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkbp:associatedWith gptkb:cancer
gptkb:Costello_syndrome
gptkb:head_and_neck_squamous_cell_carcinoma
bladder cancer
gptkbp:biologicalProcess GTPase activity
gptkbp:discoveredBy gptkb:Harold_E._Varmus
gptkb:J._Michael_Bishop
gptkbp:encodes gptkb:HRas_protein
gptkbp:Entrez_Gene_ID 3265
gptkbp:enzymeCommissionNumber 3.6.5.2
gptkbp:expressedIn human tissues
gptkbp:HGNC_ID 5173
https://www.w3.org/2000/01/rdf-schema#label HRas proto-oncogene, GTPase
gptkbp:involvedIn cell differentiation
cell proliferation
signal transduction
gptkbp:locatedOnChromosome chromosome 11
gptkbp:memberOf gptkb:Ras_subfamily
gptkb:small_GTPase_superfamily
gptkbp:mutationAssociatedWith oncogenic transformation
gptkbp:OMIM 190020
gptkbp:orthologInMouse gptkb:Hras1
Hras
gptkbp:proteinFamily gptkb:CAAX_box
gptkb:GTP-binding_domain
gptkbp:regulates gptkb:MAPK/ERK_pathway
gptkb:PI3K/AKT_pathway
gptkbp:UniProtID gptkb:P01112
gptkbp:bfsParent gptkb:human_HRAS
gptkb:3265_(HRAS)
gptkbp:bfsLayer 6