|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:BZS
gptkb:MHAM
gptkb:MMAC1
gptkb:PTEN1
gptkb:TEP1
|
|
gptkbp:approvedBy
|
gptkb:phosphatase_and_tensin_homolog
|
|
gptkbp:approvedSymbol
|
gptkb:PTEN
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Bannayan-Riley-Ruvalcaba_syndrome
gptkb:Cowden_syndrome
gptkb:Lhermitte-Duclos_disease
gptkb:P60484
gptkb:endometrial_cancer
gptkb:glioblastoma
gptkb:melanoma
prostate cancer
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000171862
5728
|
|
gptkbp:essentialGene
|
true
|
|
gptkbp:function
|
gptkb:tumor_suppressor
gptkb:protein
lipid phosphatase
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:10721
|
|
gptkbp:isTumorSuppressor
|
true
|
|
gptkbp:length
|
105kb
|
|
gptkbp:locatedOnChromosome
|
10
|
|
gptkbp:location
|
gptkb:10q23.31
|
|
gptkbp:locusType
|
gene with protein product
|
|
gptkbp:numberOfExons
|
9
|
|
gptkbp:OMIM
|
601728
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Pten
rat Pten
|
|
gptkbp:pathway
|
gptkb:PI3K-Akt_signaling_pathway
apoptosis
cell cycle regulation
cell migration
|
|
gptkbp:previousSymbols
|
gptkb:MMAC1
gptkb:TEP1
|
|
gptkbp:proteinFamily
|
phosphatases
tumor suppressors
|
|
gptkbp:RefSeq
|
gptkb:NM_000314
|
|
gptkbp:symbol
|
approved
|
|
gptkbp:UniProtID
|
gptkb:P60484
|
|
gptkbp:bfsParent
|
gptkb:secretin_receptor
|
|
gptkbp:bfsLayer
|
7
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
HGNC:10721
|