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Growth factor receptor-bound protein 2 homolog
URI:
https://gptkb.org/entity/Growth_factor_receptor-bound_protein_2_homolog
GPTKB entity
Statements (38)
Predicate
Object
gptkbp:instanceOf
gptkb:protein
gptkbp:alternativeName
gptkb:Growth_factor_receptor-bound_protein_2
gptkb:ASH
gptkb:GRB2
Adapter protein GRB2
gptkbp:associatedWith
gptkb:cancer
gptkbp:biologicalProcess
protein binding
SH2 domain binding
SH3 domain binding
gptkbp:domain
SH2 domain
SH3 domain
gptkbp:Entrez_Gene_ID
gptkb:ENSG00000177885
gptkbp:firstDescribed
1992
gptkbp:foundIn
gptkb:Homo_sapiens
gptkbp:function
adaptor protein in signal transduction
gptkbp:gene
gptkb:GRB2
gptkbp:HGNC_ID
4566
https://www.w3.org/2000/01/rdf-schema#label
Growth factor receptor-bound protein 2 homolog
gptkbp:interactsWith
gptkb:EGFR
gptkb:SHC1
gptkb:SOS1
gptkbp:involves
gptkb:EGFR_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkbp:length
217
gptkbp:locatedOnChromosome
gptkb:17q25
gptkbp:location
gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:OMIM
108355
gptkbp:orthologInMouse
gptkb:Grb2
gptkbp:PDB
gptkb:1GRI
gptkbp:RefSeq
NP_002078.2
gptkbp:regulates
cell differentiation
cell proliferation
RAS signaling
gptkbp:requires
embryonic development
gptkbp:UniProtID
gptkb:P62993
gptkbp:bfsParent
gptkb:Growth_factor_receptor-bound_protein_2
gptkbp:bfsLayer
7