Growth factor receptor-bound protein 2 homolog

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:Growth_factor_receptor-bound_protein_2 gptkb:ASH gptkb:GRB2 Adapter protein GRB2
gptkbp:associatedWith	gptkb:cancer
gptkbp:biologicalProcess	protein binding SH2 domain binding SH3 domain binding
gptkbp:domain	SH2 domain SH3 domain
gptkbp:Entrez_Gene_ID	gptkb:ENSG00000177885
gptkbp:firstDescribed	1992
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	adaptor protein in signal transduction
gptkbp:gene	gptkb:GRB2
gptkbp:HGNC_ID	4566
gptkbp:interactsWith	gptkb:EGFR gptkb:SHC1 gptkb:SOS1
gptkbp:involves	gptkb:EGFR_signaling_pathway gptkb:MAPK_signaling_pathway
gptkbp:length	217
gptkbp:locatedOnChromosome	gptkb:17q25
gptkbp:location	gptkb:cytoplasm gptkb:plasma_membrane
gptkbp:OMIM	108355
gptkbp:orthologInMouse	gptkb:Grb2
gptkbp:PDB	gptkb:1GRI
gptkbp:RefSeq	NP_002078.2
gptkbp:regulates	cell differentiation cell proliferation RAS signaling
gptkbp:requires	embryonic development
gptkbp:UniProtID	gptkb:P62993
gptkbp:bfsParent	gptkb:Growth_factor_receptor-bound_protein_2
gptkbp:bfsLayer	7
http://www.w3.org/2000/01/rdf-schema#label	Growth factor receptor-bound protein 2 homolog