|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:GSK-3_alpha
gptkb:glycogen_synthase_kinase_3_alpha
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:diabetes_mellitus
bipolar disorder
|
|
gptkbp:Entrez_Gene_ID
|
2931
ENSG00000105723
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.26
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
liver
|
|
gptkbp:fullName
|
gptkb:Glycogen_synthase_kinase-3_alpha
|
|
gptkbp:function
|
gptkb:Wnt_signaling_pathway
serine/threonine protein kinase
cellular response to insulin stimulus
regulation of glycogen metabolism
|
|
gptkbp:gene
|
gptkb:GSK3A
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
NM_001146156
NM_019884
|
|
gptkbp:HGNC_ID
|
4616
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GSK3A
|
|
gptkbp:inhibitedBy
|
gptkb:insulin
lithium
|
|
gptkbp:length
|
483
|
|
gptkbp:locatedOnChromosome
|
19q13.2
|
|
gptkbp:molecularWeight
|
51 kDa
|
|
gptkbp:OMIM
|
606784
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Gsk3a
|
|
gptkbp:pathway
|
gptkb:PI3K-Akt_signaling_pathway
gptkb:Wnt_signaling_pathway
insulin signaling pathway
|
|
gptkbp:PDB
|
gptkb:1PYX
gptkb:1Q4L
1Q5K
|
|
gptkbp:phosphorylates
|
gptkb:glycogen_synthase
gptkb:tau_protein
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:RefSeq_mRNA_ID
|
NM_019884
|
|
gptkbp:RefSeq_Protein_ID
|
NP_062826
|
|
gptkbp:relatedTo
|
gptkb:GSK3B
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P49840
|
|
gptkbp:bfsParent
|
gptkb:GSK3B
gptkb:GSK3
|
|
gptkbp:bfsLayer
|
6
|