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gptkbp:instanceOf
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gptkb:protein
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gptkbp:abbreviation
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gptkb:GPCRs
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gptkbp:discoveredBy
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gptkb:Martin_Rodbell
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gptkbp:discoveredIn
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1970s
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gptkbp:example
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gptkb:receptor_tyrosine_kinase
gptkb:angiotensin_receptor
gptkb:beta-adrenergic_receptor
gptkb:glucagon_receptor
gptkb:muscarinic_acetylcholine_receptor
gptkb:olfactory_receptor
gptkb:rhodopsin
gptkb:adrenocorticotropic_hormone_receptor
gptkb:melanocortin_receptor
cannabinoid receptor
dopamine receptor
opioid
antihistamine
chemokine receptor
free fatty acid receptor
frizzled receptor
metabotropic glutamate receptor
orphan GPCR
parathyroid hormone receptor
prostaglandin receptor
purinergic receptor
trace amine-associated receptor
vasopressin receptor
gonadotropin receptor
thyrotropin receptor
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gptkbp:foundIn
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gptkb:protists
animals
fungi
plants
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gptkbp:fullName
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gptkb:G_protein-coupled_receptors
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gptkbp:function
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signal transduction
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https://www.w3.org/2000/01/rdf-schema#label
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GPR receptors
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gptkbp:ligand
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light
hormones
neurotransmitters
peptides
odorants
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gptkbp:location
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gptkb:cell_membrane
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gptkbp:NobelPrizeYear
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gptkb:Martin_Rodbell
gptkb:Alfred_G._Gilman
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gptkbp:numberOfGenes
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over 800 in humans
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gptkbp:pathway
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G protein signaling pathway
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gptkbp:pharmacologicalImportance
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target of about 30% of all modern medicinal drugs
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gptkbp:significance
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drug targets
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gptkbp:structure
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seven transmembrane domains
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gptkbp:superfamily
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membrane receptors
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gptkbp:bfsParent
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gptkb:G_protein-coupled_receptor_superfamily
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gptkbp:bfsLayer
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7
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