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gptkbp:instanceOf
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gptkb:protein
gptkb:G_protein-coupled_receptor
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gptkbp:alternativeName
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gptkb:odorant_receptor
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gptkbp:discoveredBy
|
gptkb:Richard_Axel
gptkb:Linda_Buck
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gptkbp:discoveredIn
|
1991
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gptkbp:encodedBy
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gptkb:olfactory_receptor_gene
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gptkbp:expressedIn
|
olfactory sensory neurons
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gptkbp:foundIn
|
insects
vertebrates
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gptkbp:function
|
detect odor molecules
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|
https://www.w3.org/2000/01/rdf-schema#label
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olfactory receptor
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gptkbp:launched
|
olfactory signal transduction cascade
|
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gptkbp:ligand
|
odorant molecule
|
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gptkbp:locatedOnChromosome
|
varies by species
|
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gptkbp:location
|
gptkb:olfactory_epithelium
|
|
gptkbp:mutationAssociatedWith
|
can cause anosmia
|
|
gptkbp:NobelPrizeYear
|
gptkb:2004_Nobel_Prize_in_Physiology_or_Medicine
|
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gptkbp:numberInHumanGenome
|
~400 functional genes
|
|
gptkbp:numberInMouseGenome
|
~1000 functional genes
|
|
gptkbp:presentIn
|
gptkb:fish
birds
insects
amphibians
mammals
reptiles
|
|
gptkbp:proteinFamily
|
largest gene family in vertebrates
|
|
gptkbp:role
|
sense of smell
|
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gptkbp:structure
|
7 transmembrane alpha helices
|
|
gptkbp:transmembraneDomains
|
7
|
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gptkbp:type
|
G protein-mediated
|
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gptkbp:bfsParent
|
gptkb:G_protein-coupled_receptor
gptkb:G_protein-coupled_receptors
|
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gptkbp:bfsLayer
|
5
|