|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:activatedBy
|
cAMP production
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:diabetes_mellitus
hyperglycemia
|
|
gptkbp:binds
|
gptkb:glucagon
|
|
gptkbp:discoveredBy
|
1993
|
|
gptkbp:encodedBy
|
gptkb:GCGR_gene
|
|
gptkbp:Entrez_Gene_ID
|
2642
|
|
gptkbp:expressedIn
|
gptkb:kidney
heart
liver
adipose tissue
|
|
gptkbp:foundIn
|
gptkb:human
gptkb:mouse
right
|
|
gptkbp:function
|
regulation of glucose metabolism
activation of adenylate cyclase
|
|
gptkbp:HGNC_ID
|
4193
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
glucagon receptor
|
|
gptkbp:length
|
477 amino acids
|
|
gptkbp:locatedIn
|
gptkb:cell_membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q25
|
|
gptkbp:modulatedBy
|
antagonists
agonists
|
|
gptkbp:OMIM
|
138130
|
|
gptkbp:orthologIn
|
gptkb:mouse_Gcgr
gptkb:rat_Gcgr
|
|
gptkbp:PDB
|
5YQZ
|
|
gptkbp:structure
|
7 transmembrane domains
|
|
gptkbp:targetOfDrug
|
type 2 diabetes drugs
|
|
gptkbp:type
|
Gs protein pathway
|
|
gptkbp:UniProtID
|
P47871
|
|
gptkbp:bfsParent
|
gptkb:G_protein-coupled_receptor
gptkb:G_protein-coupled_receptors
|
|
gptkbp:bfsLayer
|
5
|