GRB2-associated-binding protein 1
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:GAB1
GRB2-associated binder 1 |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:Noonan_syndrome |
| gptkbp:discoveredBy |
late 1990s
|
| gptkbp:encodedBy |
GAB1 gene
|
| gptkbp:Entrez_Gene_ID |
9749
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
signal transduction
|
| gptkbp:gene |
gptkb:GAB1
|
| https://www.w3.org/2000/01/rdf-schema#label |
GRB2-associated-binding protein 1
|
| gptkbp:interactsWith |
gptkb:PIK3R1
gptkb:PTPN11 gptkb:SHC1 gptkb:GRB2 gptkb:MET |
| gptkbp:locatedOnChromosome |
4q31.1
|
| gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:molecularWeight |
~75 kDa
|
| gptkbp:pathway |
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway |
| gptkbp:phosphorylates |
tyrosine residues
|
| gptkbp:postTranslationalModification |
phosphorylation
|
| gptkbp:UniProtID |
Q13480
|
| gptkbp:bfsParent |
gptkb:GAB1
gptkb:Gab1 |
| gptkbp:bfsLayer |
7
|