Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:activatedBy |
growth factor withdrawal
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:diabetes neurodegenerative diseases |
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| https://www.w3.org/2000/01/rdf-schema#label |
FoxO signaling pathway
|
| gptkbp:inhibitedBy |
insulin signaling
|
| gptkbp:involves |
gptkb:14-3-3_proteins
gptkb:FOXO1 gptkb:FOXO3 gptkb:FOXO4 gptkb:FOXO6 gptkb:SGK gptkb:SIRT1 gptkb:PI3K-Akt_pathway gptkb:AMPK gptkb:JNK_pathway dephosphorylation ubiquitination acetylation FoxO transcription factors nuclear translocation of FoxO phosphorylation of FoxO proteins |
| gptkbp:KEGGID |
hsa04068
|
| gptkbp:regulates |
apoptosis
cell proliferation cell survival longevity DNA repair lipid metabolism cellular senescence mitochondrial function angiogenesis protein synthesis glucose metabolism inflammation immune response cell cycle stem cell maintenance autophagy insulin sensitivity glucose homeostasis cellular differentiation stress resistance oxidative stress resistance metabolic homeostasis |
| gptkbp:bfsParent |
gptkb:KRAS_(human)
|
| gptkbp:bfsLayer |
7
|