Fas receptor

URI: https://gptkb.org/entity/Fas_receptor

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:cell_surface_receptor gptkb:gene
gptkbp:alternativeName	gptkb:APO-1 gptkb:CD95 gptkb:TNFRSF6
gptkbp:associatedWith	gptkb:autoimmune_lymphoproliferative_syndrome gptkb:cancer apoptosis regulation
gptkbp:discoveredIn	1991
gptkbp:domain	death domain
gptkbp:encodedBy	gptkb:FAS_gene
gptkbp:Entrez_Gene_ID	355
gptkbp:expressedIn	various tissues
gptkbp:function	induces apoptosis
gptkbp:HGNC_ID	gptkb:HGNC:11920
gptkbp:interactsWith	gptkb:FADD gptkb:Fas_ligand gptkb:caspase-8
gptkbp:ligand	gptkb:Fas_ligand
gptkbp:locatedOnChromosome	10q23
gptkbp:location	gptkb:cell_membrane
gptkbp:memberOf	gptkb:tumor_necrosis_factor_receptor_superfamily
gptkbp:mutationAssociatedWith	immune system disorders cancer susceptibility
gptkbp:OMIM	134637
gptkbp:PDB	gptkb:3THM
gptkbp:regulates	cell death
gptkbp:species	gptkb:Homo_sapiens
gptkbp:structure	type I transmembrane protein
gptkbp:UniProtID	gptkb:P25445
gptkbp:bfsParent	gptkb:FAS
gptkbp:bfsLayer	5
https://www.w3.org/2000/01/rdf-schema#label	Fas receptor