|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
ACDMM
HBGF-8
KAL6
SYNCHD
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Kallmann_syndrome
developmental disorders
|
|
gptkbp:biologicalProcess
|
cell signaling
growth factor activity
organ development
|
|
gptkbp:discoveredBy
|
Richard M. Harland
|
|
gptkbp:discoveredIn
|
1994
|
|
gptkbp:encodedBy
|
FGF8 gene
|
|
gptkbp:Entrez_Gene_ID
|
2253
ENSG00000138685
|
|
gptkbp:expressedIn
|
brain
midbrain
forebrain
limb bud
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:fullName
|
Fibroblast growth factor 8
|
|
gptkbp:function
|
cell differentiation
embryonic development
cell growth
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
3666
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FGF8
|
|
gptkbp:length
|
215 amino acids
|
|
gptkbp:locatedOnChromosome
|
10q24
|
|
gptkbp:memberOf
|
gptkb:fibroblast_growth_factor_family
|
|
gptkbp:molecularWeight
|
23 kDa
|
|
gptkbp:mutationAssociatedWith
|
hypogonadotropic hypogonadism
craniofacial defects
|
|
gptkbp:OMIM
|
600483
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
|
|
gptkbp:PDB
|
2FDB
|
|
gptkbp:recipient
|
gptkb:FGFR3
gptkb:FGFR1
gptkb:FGFR4
gptkb:FGFR2
|
|
gptkbp:regulates
|
neural development
anterior-posterior patterning
limb outgrowth
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:UniProtID
|
P55075
|
|
gptkbp:bfsParent
|
gptkb:FGFR1
|
|
gptkbp:bfsLayer
|
6
|