SRF (serum response factor)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:transcription_factor gptkb:protein
gptkbp:alias	gptkb:SRF gptkb:Serum_response_factor MADS box transcription enhancer factor 2
gptkbp:alternativeSplicing	yes
gptkbp:binds	gptkb:serum_response_element_(SRE)
gptkbp:discoveredBy	gptkb:Richard_Treisman
gptkbp:discoveredIn	1986
gptkbp:domain	gptkb:MADS-box
gptkbp:encodedBy	gptkb:SRF_gene
gptkbp:Entrez_Gene_ID	6722
gptkbp:expressedIn	gptkb:skeletal_muscle gptkb:neurons heart smooth muscle
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	regulation of gene expression regulation of immediate-early genes regulation of muscle-specific genes
gptkbp:interactsWith	gptkb:ELK1 gptkb:MRTF-A gptkb:MRTF-B TCF family proteins
gptkbp:length	508 amino acids
gptkbp:locatedOnChromosome	gptkb:chromosome_6p21.1
gptkbp:molecularWeight	51 kDa
gptkbp:OMIM	600589
gptkbp:orthologIn	gptkb:Mus_musculus gptkb:Drosophila_melanogaster gptkb:Rattus_norvegicus
gptkbp:PDB	1HBX
gptkbp:phosphorylates	gptkb:MAPK gptkb:ERK
gptkbp:regulates	gptkb:c-fos_gene cell differentiation wound healing angiogenesis cell growth cell migration muscle development myogenesis cellular proliferation actin cytoskeleton genes cytoskeletal gene expression neuronal growth immediate-early response genes
gptkbp:subcellularLocation	gptkb:nucleus
gptkbp:UniProtID	P11831
gptkbp:bfsParent	gptkb:ELK1 gptkb:Elk-1
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	SRF (serum response factor)