|
gptkbp:instanceOf
|
gptkb:protein
cell surface receptor
|
|
gptkbp:alsoKnownAs
|
gptkb:CD26
dipeptidyl peptidase-4
|
|
gptkbp:discoveredBy
|
Hans-Dieter Lang
|
|
gptkbp:discoveredIn
|
1966
|
|
gptkbp:encodedBy
|
DPP4 gene
|
|
gptkbp:Entrez_Gene_ID
|
1803
|
|
gptkbp:enzymeClassification
|
EC 3.4.14.5
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:T_cells
gptkb:kidney
gptkb:placenta
gptkb:prostate
liver
bone marrow
pancreas
endothelial cells
intestine
epithelial cells
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:function
|
regulates glucose metabolism
cleaves dipeptides from polypeptides
involved in immune regulation
|
|
gptkbp:HGNC_ID
|
HGNC:3009
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DPP4 receptor
|
|
gptkbp:inhibitedBy
|
gptkb:alogliptin
gptkb:sitagliptin
gptkb:saxagliptin
gptkb:vildagliptin
linagliptin
|
|
gptkbp:interactsWith
|
gptkb:fibronectin
gptkb:adenosine_deaminase
gptkb:MERS-CoV_spike_protein
collagen
|
|
gptkbp:ligand
|
gptkb:GLP-1
gptkb:GIP
|
|
gptkbp:locatedOnChromosome
|
gptkb:2q24.2
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
110 kDa
|
|
gptkbp:OMIM
|
102720
|
|
gptkbp:PDB
|
4A5S
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:role
|
gptkb:cancer
gptkb:type_2_diabetes
gptkb:MERS-CoV_infection
immune disorders
|
|
gptkbp:structure
|
gptkb:protein
homodimer
|
|
gptkbp:target
|
antidiabetic drugs
DPP4 inhibitors
|
|
gptkbp:UniProtID
|
gptkb:P27487
|
|
gptkbp:bfsParent
|
gptkb:MERS-CoV_spike_protein
|
|
gptkbp:bfsLayer
|
7
|