Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:virus
|
| gptkbp:binds |
gptkb:DPP4_receptor
|
| gptkbp:cleavage |
host proteases
|
| gptkbp:composedOf |
gptkb:S1_subunit
gptkb:S2_subunit |
| gptkbp:enables |
membrane fusion
|
| gptkbp:encodedBy |
gptkb:S_gene
|
| gptkbp:foundIn |
gptkb:Middle_East_respiratory_syndrome_coronavirus
|
| gptkbp:function |
mediates viral entry into host cells
|
| gptkbp:glycosylation |
yes
|
| gptkbp:hasFusionPeptide |
gptkb:S2_subunit
|
| gptkbp:hasReceptorBindingDomain |
gptkb:S1_subunit
|
| https://www.w3.org/2000/01/rdf-schema#label |
MERS-CoV spike protein
|
| gptkbp:importantFor |
immune evasion
host specificity |
| gptkbp:molecularWeight |
~180 kDa
|
| gptkbp:PDB |
gptkb:5X59
gptkb:6Q04 |
| gptkbp:structure |
trimeric glycoprotein
|
| gptkbp:target |
neutralizing antibodies
|
| gptkbp:usedIn |
vaccine development
|
| gptkbp:bfsParent |
gptkb:SARS-CoV-2_spike_protein
|
| gptkbp:bfsLayer |
6
|