GLP-1

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf peptide
gptkbp:agonistDrugs gptkb:albiglutide
gptkb:exenatide
gptkb:liraglutide
gptkb:lixisenatide
gptkb:semaglutide
gptkb:dulaglutide
gptkbp:category incretin hormone
gptkbp:degradedBy gptkb:DPP-4_enzyme
gptkbp:discoveredIn 1980s
gptkbp:fullName Glucagon-like peptide-1
gptkbp:function slows gastric emptying
reduces appetite
stimulates insulin secretion
inhibits glucagon secretion
gptkbp:gene gptkb:GCG_gene
gptkbp:halfLife 1-2 minutes
https://www.w3.org/2000/01/rdf-schema#label GLP-1
gptkbp:orthologIn GLP-2
gptkbp:predecessor proglucagon
gptkbp:producedBy L-cells of the intestine
gptkbp:recipient gptkb:GLP-1_receptor
gptkbp:structure amino acid peptide
gptkbp:usedIn treatment of obesity
treatment of type 2 diabetes
gptkbp:bfsParent gptkb:insulin
gptkbp:bfsLayer 6