Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
DPP-4 inhibitor |
| gptkbp:approvalYear |
2010
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
| gptkbp:ATCCode |
A10BH04
|
| gptkbp:brand |
gptkb:Nesina
|
| gptkbp:CASNumber |
850649-62-6
|
| gptkbp:chemicalFormula |
C18H21N5O2
|
| gptkbp:combines |
gptkb:metformin
gptkb:pioglitazone |
| gptkbp:contraindication |
gptkb:diabetic_ketoacidosis
type 1 diabetes |
| gptkbp:developer |
gptkb:Takeda_Pharmaceutical_Company
|
| gptkbp:eliminationHalfLife |
21 hours
|
| gptkbp:excretion |
renal
|
| https://www.w3.org/2000/01/rdf-schema#label |
alogliptin
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits dipeptidyl peptidase-4
|
| gptkbp:metabolism |
minimal hepatic
|
| gptkbp:molecularWeight |
339.39 g/mol
|
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
headache
joint pain upper respiratory tract infection nasopharyngitis |
| gptkbp:usedFor |
gptkb:type_2_diabetes_mellitus
|
| gptkbp:bfsParent |
gptkb:DPP-4_enzyme
gptkb:DPP-4_inhibitors gptkb:Nesina |
| gptkbp:bfsLayer |
7
|