DNA-PK

URI: https://gptkb.org/entity/DNA-PK

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:DNA-PK_holoenzyme gptkb:DNA-dependent_protein_kinase_complex
gptkbp:associatedWith	gptkb:cancer
gptkbp:component	gptkb:DNA-PKcs gptkb:Ku70 gptkb:Ku80
gptkbp:discoveredBy	gptkb:David_J._Chen
gptkbp:EC_number	2.7.11.1
gptkbp:enzymeClassification	serine/threonine protein kinase
gptkbp:fullName	gptkb:DNA-dependent_protein_kinase
gptkbp:function	gptkb:non-homologous_end_joining DNA double-strand break repair
gptkbp:gene	gptkb:PRKDC gptkb:XRCC5 gptkb:XRCC6
gptkbp:GO_term	gptkb:GO:0004674
gptkbp:inhibitedBy	gptkb:NU7441 gptkb:wortmannin
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:PDB	5LUQ
gptkbp:relatedTo	gptkb:V(D)J_recombination
gptkbp:subcellularLocation	gptkb:nucleus
gptkbp:UniProtID	gptkb:P78527
gptkbp:bfsParent	gptkb:LY294002
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	DNA-PK