Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:Oncology
|
| gptkbp:components |
Ku protein
DNA-PKcs |
| gptkbp:discovered_by |
1990s
|
| gptkbp:function |
DNA repair
|
| https://www.w3.org/2000/01/rdf-schema#label |
DNA-PK
|
| gptkbp:initiated_by |
DNA-PK inhibitors
|
| gptkbp:interacts_with |
gptkb:DNA
gptkb:ATM_protein p53 protein |
| gptkbp:involved_in |
gptkb:neurodegenerative_diseases
DNA damage response aging cellular homeostasis cellular metabolism cellular transport protein synthesis signal transduction cellular proliferation transcription regulation tumorigenesis non-homologous end joining cellular differentiation cellular signaling pathways cellular adhesion cellular communication stem cell maintenance cellular repair mechanisms metabolic regulation telomere maintenance cellular aging processes cellular differentiation pathways cellular growth control cellular repair pathways cellular signaling networks cellular immune responses immune system development cellular apoptosis cellular stress response pathways cellular migration genomic integrity viral infection response V(D) J recombination |
| gptkbp:location |
gptkb:Atom
|
| gptkbp:related_to |
apoptosis
cellular stress response chromosomal stability double-strand break repair radiation response |
| gptkbp:research_areas |
gptkb:Genetics
molecular biology oncology |
| gptkbp:role |
cell cycle regulation
immune response |
| gptkbp:bfsParent |
gptkb:MRE11
|
| gptkbp:bfsLayer |
8
|