DNA-PK

URI: https://gptkb.org/entity/DNA-PK
GPTKB entity
Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:DNA-PK_holoenzyme
gptkb:DNA-dependent_protein_kinase_complex
gptkbp:associatedWith gptkb:cancer
gptkbp:component gptkb:DNA-PKcs
gptkb:Ku70
gptkb:Ku80
gptkbp:discoveredBy gptkb:David_J._Chen
gptkbp:EC_number 2.7.11.1
gptkbp:enzymeClassification serine/threonine protein kinase
gptkbp:fullName gptkb:DNA-dependent_protein_kinase
gptkbp:function gptkb:non-homologous_end_joining
DNA double-strand break repair
gptkbp:gene gptkb:PRKDC
gptkb:XRCC5
gptkb:XRCC6
gptkbp:GO_term gptkb:GO:0004674
https://www.w3.org/2000/01/rdf-schema#label DNA-PK
gptkbp:inhibitedBy gptkb:NU7441
gptkb:wortmannin
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 5LUQ
gptkbp:relatedTo gptkb:V(D)J_recombination
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:UniProtID gptkb:P78527
gptkbp:bfsParent gptkb:LY294002
gptkbp:bfsLayer 5