Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:XRCC6
|
| gptkbp:binds |
DNA ends
|
| gptkbp:component |
Ku heterodimer
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
XRCC6 gene
|
| gptkbp:formsComplexWith |
gptkb:Ku80
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ku70
|
| gptkbp:interactsWith |
gptkb:DNA-PKcs
Ligase IV XRCC4 |
| gptkbp:involvedIn |
gptkb:non-homologous_end_joining
DNA double-strand break repair |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:molecularWeight |
~70 kDa
|
| gptkbp:mutationAssociatedWith |
immunodeficiency
cancer susceptibility |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae |
| gptkbp:PDB |
1JEQ
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination acetylation |
| gptkbp:regulates |
apoptosis
|
| gptkbp:requires |
genome stability
|
| gptkbp:bfsParent |
gptkb:DNA-PK
|
| gptkbp:bfsLayer |
6
|