Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic recombination process
|
| gptkbp:cause |
lymphoid malignancies
chromosomal translocations |
| gptkbp:discoveredBy |
gptkb:Susumu_Tonegawa
|
| gptkbp:enables |
antibody diversity
T cell receptor diversity |
| gptkbp:firstDescribed |
1976
|
| https://www.w3.org/2000/01/rdf-schema#label |
V(D)J recombination
|
| gptkbp:involves |
immunoglobulin genes
D gene segments J gene segments T cell receptor genes V gene segments |
| gptkbp:mediatedBy |
gptkb:RAG1_protein
RAG2 protein |
| gptkbp:occurredIn |
vertebrates
lymphocyte development |
| gptkbp:regulates |
recombination signal sequences
|
| gptkbp:requires |
gptkb:adaptive_immune_system
|
| gptkbp:result |
unique antigen receptors
|
| gptkbp:studiedIn |
immunology
|
| gptkbp:bfsParent |
gptkb:DNA-PK
gptkb:D_region gptkb:T_cell_receptor_(TCR) |
| gptkbp:bfsLayer |
6
|