V(D)J recombination

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:genetic_recombination_process
gptkbp:cause lymphoid malignancies
chromosomal translocations
gptkbp:discoveredBy gptkb:Susumu_Tonegawa
gptkbp:enables antibody diversity
T cell receptor diversity
gptkbp:firstDescribed 1976
gptkbp:involves immunoglobulin genes
D gene segments
J gene segments
T cell receptor genes
V gene segments
gptkbp:mediatedBy gptkb:RAG1_protein
RAG2 protein
gptkbp:occurredIn vertebrates
lymphocyte development
gptkbp:regulates recombination signal sequences
gptkbp:requires gptkb:adaptive_immune_system
gptkbp:result unique antigen receptors
gptkbp:studiedIn immunology
gptkbp:bfsParent gptkb:DNA-PK
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label V(D)J recombination