Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:XRCC5
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
XRCC5 gene
|
| gptkbp:form |
Ku heterodimer
|
| gptkbp:formsComplexWith |
gptkb:Ku70
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
gptkb:non-homologous_end_joining
DNA double-strand break repair |
| https://www.w3.org/2000/01/rdf-schema#label |
Ku80
|
| gptkbp:interactsWith |
gptkb:DNA-PKcs
Ligase IV XRCC4 |
| gptkbp:involvedIn |
gptkb:V(D)J_recombination
telomere maintenance |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
chromosome 2q33-q34
|
| gptkbp:molecularWeight |
~80 kDa
|
| gptkbp:mutationAssociatedWith |
immunodeficiency
cancer susceptibility |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus Saccharomyces cerevisiae (as YKU80) |
| gptkbp:PDB |
1JEQ
|
| gptkbp:requires |
genome stability
|
| gptkbp:UniProtID |
P13010
|
| gptkbp:bfsParent |
gptkb:DNA-PK
|
| gptkbp:bfsLayer |
6
|