Cdk1

GPTKB entity

Statements (69)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:activatedBy gptkb:cyclin_A
gptkb:cyclin_B
gptkbp:alias gptkb:cell_division_control_protein_2_homolog
gptkb:p34_protein_kinase
gptkb:CDC2
CDK1A
CDK1B
CDK1L1
CDK1L10
CDK1L11
CDK1L12
CDK1L13
CDK1L14
CDK1L15
CDK1L16
CDK1L17
CDK1L18
CDK1L19
CDK1L2
CDK1L20
CDK1L21
CDK1L22
CDK1L23
CDK1L24
CDK1L25
CDK1L26
CDK1L27
CDK1L28
CDK1L29
CDK1L3
CDK1L30
CDK1L4
CDK1L5
CDK1L6
CDK1L7
CDK1L8
CDK1L9
gptkbp:discoveredBy gptkb:Paul_Nurse
gptkbp:EC_number 2.7.11.22
gptkbp:Entrez_Gene_ID gptkb:ENSG00000170312
gptkbp:expressedIn all proliferating cells
gptkbp:fullName gptkb:Cyclin-dependent_kinase_1
gptkbp:function regulation of cell cycle
mitosis regulation
gptkbp:gene gptkb:CDK1
gptkbp:HGNC_ID HGNC:1722
https://www.w3.org/2000/01/rdf-schema#label Cdk1
gptkbp:inhibitedBy gptkb:p21
gptkb:p27
Myt1 kinase
Wee1 kinase
gptkbp:locatedOnChromosome chromosome 10q21.2
gptkbp:molecularWeight 34 kDa
gptkbp:mutationAssociatedWith cell cycle arrest
defective mitosis
gptkbp:organism gptkb:Homo_sapiens
gptkbp:ortholog_in_fission_yeast gptkb:cdc2
gptkbp:orthologInYeast gptkb:CDC28
gptkbp:PDB 4YC3
gptkbp:phosphorylates various substrates involved in cell cycle
gptkbp:requires mitotic exit
G2/M transition
mitotic entry
gptkbp:structure serine/threonine kinase domain
gptkbp:UniProtID gptkb:P06493
gptkbp:bfsParent gptkb:CDK1_gene
gptkbp:bfsLayer 6