|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:ECT2_proto-oncogene
gptkb:KIAA0131
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
glioma
|
|
gptkbp:biologicalProcess
|
cell cycle regulation
Rho GTPase exchange factor activity
mitotic spindle formation
|
|
gptkbp:domain
|
gptkb:PH_domain
gptkb:BRCT_domain
DH domain
|
|
gptkbp:encodedBy
|
gptkb:ECT2_gene
|
|
gptkbp:Entrez_Gene_ID
|
1894
ENSG00000133216
|
|
gptkbp:fullName
|
gptkb:Epithelial_cell_transforming_sequence_2_oncogene
|
|
gptkbp:function
|
regulation of cell division
guanine nucleotide exchange factor (GEF)
regulation of cytokinesis
|
|
gptkbp:gene
|
gptkb:ECT2
|
|
gptkbp:GO
|
GO:0005525
GO:0005089
GO:0007067
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ect2
|
|
gptkbp:interactsWith
|
gptkb:RhoA
gptkb:Cdk1
gptkb:MgcRacGAP
|
|
gptkbp:length
|
883 amino acids
|
|
gptkbp:locatedOnChromosome
|
3q26.31
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Ect2_(mouse)
gptkb:Ect2_(rat)
|
|
gptkbp:PDB
|
gptkb:2YTW
|
|
gptkbp:phosphorylates
|
Serine 345
Threonine 341
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:RefSeq
|
NM_018097
|
|
gptkbp:UniProtID
|
Q9H8V3
|
|
gptkbp:bfsParent
|
gptkb:GEFs_(guanine_nucleotide_exchange_factors)
|
|
gptkbp:bfsLayer
|
6
|