Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:CDK1
|
| gptkbp:biologicalProcess |
protein serine/threonine kinase activity
|
| gptkbp:discoveredBy |
gptkb:Paul_Nurse
gptkb:Tim_Hunt |
| gptkbp:enzymeClassification |
EC 2.7.11.22
|
| gptkbp:formsComplexWith |
gptkb:cyclin_B
|
| gptkbp:function |
regulation of cell cycle
|
| gptkbp:gene |
gptkb:CDK1
|
| https://www.w3.org/2000/01/rdf-schema#label |
p34 protein kinase
|
| gptkbp:involves |
mitosis
G2/M transition |
| gptkbp:locatedOnChromosome |
gptkb:10q21.2
|
| gptkbp:mutationAssociatedWith |
cell cycle arrest
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInYeast |
gptkb:cdc2
|
| gptkbp:phosphorylates |
gptkb:histone_H1
gptkb:p53 lamin proteins |
| gptkbp:regulates |
activated by cyclin binding
activated by dephosphorylation at Thr14 and Tyr15 inhibited by phosphorylation at Tyr15 |
| gptkbp:requires |
cell division
|
| gptkbp:subcellularLocation |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:bfsParent |
gptkb:CDK1_gene
gptkb:CDK1 |
| gptkbp:bfsLayer |
6
|