Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:PTTG
gptkb:pituitary_tumor-transforming_gene_protein |
| gptkbp:degradation_triggers |
activation of separase
|
| gptkbp:degradedBy |
gptkb:anaphase-promoting_complex
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
inhibits separase
|
| gptkbp:gene |
gptkb:PTTG1
|
| https://www.w3.org/2000/01/rdf-schema#label |
securin
|
| gptkbp:interactsWith |
gptkb:separase
|
| gptkbp:involves |
meiosis
mitosis |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:molecularWeight |
~23 kDa
|
| gptkbp:overexpressedIn |
tumorigenesis
|
| gptkbp:phosphorylates |
gptkb:Cdk1
|
| gptkbp:regulates |
chromosome segregation
|
| gptkbp:role_in_cell_cycle |
regulates sister chromatid separation
|
| gptkbp:bfsParent |
gptkb:Anaphase-Promoting_Complex
gptkb:APC_complex |
| gptkbp:bfsLayer |
6
|