|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:cofactor
|
hemoglobin
|
|
gptkbp:discoveredBy
|
biochemical studies
|
|
gptkbp:encodes
|
gptkb:cytochrome_P450_enzymes
|
|
gptkbp:enzymeClassification
|
oxidoreductase
|
|
gptkbp:expressedIn
|
liver
other tissues
|
|
gptkbp:firstDescribed
|
1970s
|
|
gptkbp:foundIn
|
humans
other mammals
|
|
gptkbp:fullName
|
Cytochrome P450 family 2
|
|
gptkbp:function
|
drug metabolism
xenobiotic metabolism
|
|
gptkbp:hasPolymorphism
|
yes
|
|
gptkbp:HGNC_ID
|
2592
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CYP2
|
|
gptkbp:involvedIn
|
phase I metabolism
|
|
gptkbp:locatedOnChromosome
|
varies by subfamily
|
|
gptkbp:memberOf
|
gptkb:cytochrome_P450_superfamily
|
|
gptkbp:notable_for
|
gptkb:CYP2C9
gptkb:CYP2C19
gptkb:CYP2A6
gptkb:CYP2D6
CYP2E1
|
|
gptkbp:OMIM
|
124060
|
|
gptkbp:orthologIn
|
mice
rats
other vertebrates
|
|
gptkbp:regulates
|
inducible by drugs
inhibited by drugs
|
|
gptkbp:relatedTo
|
pharmacogenomics
adverse drug reactions
|
|
gptkbp:significance
|
personalized medicine
drug interactions
|
|
gptkbp:subfamily
|
gptkb:CYP2D
gptkb:CYP2A
CYP2C
CYP2E
CYP2B
CYP2F
CYP2J
CYP2R
CYP2S
CYP2U
|
|
gptkbp:substrate
|
endogenous compounds
environmental chemicals
various drugs
|
|
gptkbp:bfsParent
|
gptkb:cytochrome_P450_enzymes
gptkb:cytochrome_P450_superfamily
gptkb:cytochrome_P450
gptkb:CYP1
|
|
gptkbp:bfsLayer
|
6
|