|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:absorptionMaximum
|
450 nm
|
|
gptkbp:alsoKnownAs
|
gptkb:cytochrome_P450
|
|
gptkbp:contains
|
heme as a cofactor
|
|
gptkbp:discoveredBy
|
gptkb:M._Klingenberg
|
|
gptkbp:discoveredIn
|
1958
|
|
gptkbp:encodedBy
|
CYP genes
|
|
gptkbp:foundIn
|
gptkb:Bacteria
archaea
eukaryotes
|
|
gptkbp:function
|
catalyzes oxidation of organic substances
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P450
|
|
gptkbp:importantFor
|
metabolism of drugs
biosynthesis of hormones
detoxification of xenobiotics
|
|
gptkbp:involvedIn
|
synthesis of cholesterol
drug metabolism
synthesis of steroids
synthesis of lipids
|
|
gptkbp:presentIn
|
gptkb:gallbladder
gptkb:thyroid
gptkb:cancer
gptkb:skin
gptkb:pituitary_gland
gptkb:skeletal_muscle
gptkb:adrenal_gland
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
gptkb:thymus
blood
brain
eye
heart
liver
lymph nodes
spleen
bladder
bone marrow
colon
esophagus
pancreas
salivary gland
stomach
uterus
intestine
ear
|
|
gptkbp:structure
|
contains iron atom in heme group
|
|
gptkbp:subfamily
|
gptkb:CYP1
gptkb:CYP2
gptkb:CYP3
gptkb:CYP4
|
|
gptkbp:bfsParent
|
gptkb:AT4G25000
|
|
gptkbp:bfsLayer
|
7
|