|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CANN6
gptkb:CB1R
gptkb:CNR
gptkb:CB1
|
|
gptkbp:associatedWith
|
gptkb:depression
addiction
epilepsy
memory
schizophrenia
obesity
pain modulation
psychiatric disorders
appetite regulation
|
|
gptkbp:chromosomeArm
|
6q15
|
|
gptkbp:discoveredBy
|
gptkb:Lisa_Matsuda
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodes
|
gptkb:CB1_receptor
|
|
gptkbp:Entrez_Gene_ID
|
1268
ENSG00000118432
|
|
gptkbp:expressedIn
|
brain
central nervous system
peripheral tissues
|
|
gptkbp:fullName
|
gptkb:cannabinoid_receptor_1
|
|
gptkbp:function
|
gptkb:G_protein-coupled_receptor
mediates effects of cannabinoids
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
2159
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CNR1
|
|
gptkbp:inhibitedBy
|
gptkb:adenylate_cyclase
|
|
gptkbp:length
|
472 amino acids
|
|
gptkbp:locatedOnChromosome
|
6
|
|
gptkbp:location
|
gptkb:plasma_membrane
presynaptic terminal
|
|
gptkbp:modulatedBy
|
gptkb:potassium_channels
calcium channels
|
|
gptkbp:OMIM
|
114610
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Cnr1
|
|
gptkbp:pathway
|
gptkb:endocannabinoid_signaling_pathway
gptkb:retrograde_endocannabinoid_signaling
|
|
gptkbp:pharmacologicalAgonist
|
gptkb:CP_55,940
gptkb:HU-210
gptkb:WIN_55,212-2
|
|
gptkbp:pharmacologicalAntagonist
|
gptkb:SR141716A
gptkb:rimonabant
|
|
gptkbp:product
|
gptkb:cannabinoid_receptor_type_1
|
|
gptkbp:proteinFamily
|
gptkb:endocannabinoid_system
gptkb:G_protein-coupled_receptor
|
|
gptkbp:regulates
|
gptkb:synaptic_plasticity
neurotransmitter release
|
|
gptkbp:target
|
gptkb:THC
gptkb:anandamide
synthetic cannabinoids
|
|
gptkbp:UniProtID
|
gptkb:P21554
|
|
gptkbp:bfsParent
|
gptkb:CB1
|
|
gptkbp:bfsLayer
|
6
|