|
gptkbp:instanceOf
|
ion channel
|
|
gptkbp:activatedBy
|
ligands
voltage
intracellular signals
|
|
gptkbp:blockedIn
|
gptkb:4-aminopyridine
gptkb:tetraethylammonium
barium ions
|
|
gptkbp:component
|
resting membrane potential
action potential repolarization
|
|
gptkbp:discoveredBy
|
gptkb:Bernard_Katz
|
|
gptkbp:dysregulationAssociatedWith
|
gptkb:Andersen-Tawil_syndrome
gptkb:arrhythmia
epilepsy
ataxia
long QT syndrome
|
|
gptkbp:encodedBy
|
gptkb:KCN_gene_family
|
|
gptkbp:foundIn
|
gptkb:Bacteria
animals
fungi
plants
|
|
gptkbp:function
|
allow selective flow of potassium ions across cell membranes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
potassium channels
|
|
gptkbp:modulatedBy
|
gptkb:ATP
gptkb:G-proteins
calcium
phosphorylation
pH
oxygen tension
|
|
gptkbp:permeableTo
|
selective for K+
|
|
gptkbp:regulates
|
heart rate
muscle contraction
neuronal excitability
membrane potential
hormone secretion
|
|
gptkbp:requires
|
gptkb:judge
immune response
insulin secretion
renal function
neuronal signaling
cardiac function
cell volume regulation
muscle function
|
|
gptkbp:structure
|
tetrameric
|
|
gptkbp:subclassOf
|
gptkb:voltage-gated_potassium_channel
gptkb:two-pore-domain_potassium_channel
gptkb:voltage-gated_ion_channel
transmembrane protein
inward-rectifier potassium channel
|
|
gptkbp:bfsParent
|
gptkb:GABA_B_receptor
gptkb:HGNC:6407
|
|
gptkbp:bfsLayer
|
6
|