Statements (80)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:abbreviation |
gptkb:CB1
|
| gptkbp:binds |
gptkb:tetrahydrocannabinol
gptkb:2-arachidonoylglycerol gptkb:anandamide synthetic cannabinoids |
| gptkbp:discoveredIn |
1990
|
| gptkbp:encodedBy |
gptkb:CNR1_gene
|
| gptkbp:enemyOf |
gptkb:CP_55,940
gptkb:HU-210 gptkb:WIN_55,212-2 gptkb:SR141716A gptkb:rimonabant |
| gptkbp:expressedIn |
gptkb:hepatocytes
neurons muscle cells astrocytes adipocytes |
| gptkbp:foundIn |
gptkb:skeletal_muscle
gptkb:spinal_cord brain gastrointestinal tract central nervous system liver adipose tissue peripheral nervous system |
| gptkbp:function |
involved in appetite regulation
involved in memory involved in mood regulation involved in pain regulation modulates neurotransmitter release |
| gptkbp:HGNC_ID |
2159
|
| https://www.w3.org/2000/01/rdf-schema#label |
cannabinoid receptor type 1
|
| gptkbp:locatedOn |
gptkb:chromosome_6
|
| gptkbp:modulatedBy |
adrenaline release
growth hormone release gonadotropin release oxytocin release prolactin release vasopressin release dopamine release histamine release GABA release acetylcholine release aldosterone release angiotensin release calcitonin release chemokine release cholecystokinin release corticotropin-releasing hormone release cortisol release endothelin release erythropoietin release ghrelin release glutamate release growth factor release insulin release interferon release interleukin release leptin release melatonin release noradrenaline release norepinephrine release opioid peptide release parathyroid hormone release renin release serotonin release substance P release thyroid hormone release tumor necrosis factor release |
| gptkbp:OMIM |
114610
|
| gptkbp:orthologIn |
gptkb:mouse_Cnr1
|
| gptkbp:partOf |
gptkb:endocannabinoid_system
|
| gptkbp:relatedTo |
gptkb:cannabinoid_receptor_type_2
|
| gptkbp:structure |
seven transmembrane domains
|
| gptkbp:UniProtID |
gptkb:P21554
|
| gptkbp:bfsParent |
gptkb:CNR1
gptkb:CNR1_gene |
| gptkbp:bfsLayer |
7
|