CB1 receptor

GPTKB entity

Statements (52)
Predicate Object
gptkbp:instanceOf gptkb:G_protein-coupled_receptor
cannabinoid receptor
gptkbp:activatedBy gptkb:THC
gptkb:2-arachidonoylglycerol
gptkb:anandamide
gptkbp:alternativeName gptkb:CNR1
Cannabinoid receptor type 1
gptkbp:discoveredIn 1990
gptkbp:encodedBy gptkb:CNR1_gene
gptkbp:enemyOf gptkb:THC
gptkb:2-AG
gptkb:SR141716A
gptkb:anandamide
gptkb:rimonabant
gptkb:AM251
gptkbp:expressedIn gptkb:oligodendrocytes
neurons
astrocytes
gptkbp:foundIn gptkb:skeletal_muscle
brain
gastrointestinal tract
central nervous system
liver
adipose tissue
peripheral nervous system
reproductive organs
gptkbp:function memory
motor control
mood regulation
modulation of neurotransmitter release
pain sensation
regulation of appetite
https://www.w3.org/2000/01/rdf-schema#label CB1 receptor
gptkbp:locatedOnChromosome gptkb:chromosome_6
gptkbp:molecularWeight 53 kDa
gptkbp:OMIM 114610
gptkbp:relatedTo gptkb:CB2_receptor
gptkbp:significance target for anti-obesity drugs
target for neurodegenerative disease therapy
target for pain management
target for psychiatric disorder treatment
gptkbp:structure seven transmembrane domains
gptkbp:type activation of MAP kinase pathway
inhibition of adenylate cyclase
modulation of ion channels
gptkbp:UniProtID gptkb:P21554
gptkbp:bfsParent gptkb:JWH_cannabinoids
gptkb:endocannabinoid_system
gptkb:CB1_receptor_(indirect)
gptkb:D8
gptkb:THC
gptkbp:bfsLayer 6