|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:alternativeName
|
gptkb:CB1_receptor
gptkb:CNR1_protein
gptkb:CB1
|
|
gptkbp:biologicalProcess
|
G protein-coupled receptor activity
cannabinoid receptor activity
|
|
gptkbp:discoveredBy
|
1990
|
|
gptkbp:expressedIn
|
neurons
astrocytes
adipocytes
liver cells
|
|
gptkbp:foundIn
|
brain
gastrointestinal tract
central nervous system
liver
adipose tissue
peripheral nervous system
|
|
gptkbp:gene
|
gptkb:CNR1
|
|
gptkbp:HGNC_ID
|
2159
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
cannabinoid receptor 1
|
|
gptkbp:involves
|
memory
motor control
neuromodulation
appetite regulation
mood regulation
pain regulation
|
|
gptkbp:ligand
|
gptkb:tetrahydrocannabinol
gptkb:2-arachidonoylglycerol
gptkb:anandamide
|
|
gptkbp:locatedOnChromosome
|
6q15
|
|
gptkbp:OMIM
|
114610
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:relatedTo
|
gptkb:cannabinoid_receptor_2
gptkb:endocannabinoid_system
|
|
gptkbp:signal_transduction
|
activates MAP kinase pathway
inhibits adenylate cyclase
modulates ion channels
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structureType
|
seven-transmembrane domain protein
|
|
gptkbp:targetOfDrug
|
gptkb:THC
gptkb:rimonabant
synthetic cannabinoids
|
|
gptkbp:UniProtID
|
gptkb:P21554
|
|
gptkbp:bfsParent
|
gptkb:CB1
|
|
gptkbp:bfsLayer
|
6
|