|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CB1
gptkb:CNR1
gptkb:Cannabinoid_receptor_1
|
|
gptkbp:associatedWith
|
memory
pain modulation
motor control
mood
appetite regulation
psychoactive effects of cannabis
|
|
gptkbp:category
|
gptkb:cannabinoid_receptors
gptkb:G_protein-coupled_receptors
membrane proteins
|
|
gptkbp:discoveredBy
|
gptkb:Lisa_Matsuda
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodedBy
|
gptkb:CNR1_gene
|
|
gptkbp:enemyOf
|
gptkb:SR141716A
gptkb:rimonabant
|
|
gptkbp:fullName
|
Cannabinoid receptor type 1
|
|
gptkbp:function
|
gptkb:G_protein-coupled_receptor
mediates effects of cannabinoids
binds endocannabinoids
|
|
gptkbp:gene
|
gptkb:CNR1
|
|
gptkbp:HGNC_ID
|
2159
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CB1R
|
|
gptkbp:ligand
|
gptkb:THC
gptkb:2-arachidonoylglycerol
gptkb:anandamide
|
|
gptkbp:locatedOnChromosome
|
6q15
|
|
gptkbp:location
|
gptkb:skeletal_muscle
brain
central nervous system
liver
adipose tissue
peripheral nervous system
|
|
gptkbp:OMIM
|
114610
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:5U09
gptkb:6N4B
gptkb:6N4C
5TGZ
6KQI
|
|
gptkbp:structure
|
seven transmembrane domains
|
|
gptkbp:UniProtID
|
gptkb:P21554
|
|
gptkbp:bfsParent
|
gptkb:CNR1
gptkb:CNR1_gene
|
|
gptkbp:bfsLayer
|
7
|