|
gptkbp:instanceOf
|
gptkb:Cell
|
|
gptkbp:contactWith
|
gptkb:bile_canaliculi
sinusoids
|
|
gptkbp:damageCauses
|
gptkb:liver_disease
|
|
gptkbp:expressedIn
|
gptkb:cytochrome_P450_enzymes
|
|
gptkbp:firstDescribed
|
gptkb:Karl_Wilhelm_von_Kupffer
|
|
gptkbp:foundIn
|
liver
|
|
gptkbp:function
|
protein synthesis
detoxification
metabolism of carbohydrates
metabolism of lipids
bile production
metabolism of amino acids
|
|
gptkbp:hasNucleus
|
gptkb:single
binucleated (sometimes)
|
|
gptkbp:infects
|
gptkb:malaria_parasite
hepatitis viruses
|
|
gptkbp:lifespan
|
5 months
|
|
gptkbp:location
|
gptkb:hepatic_lobule
|
|
gptkbp:numberOfLocations
|
gptkb:vitamin_A
gptkb:glycogen
iron
vitamin B12
|
|
gptkbp:origin
|
endoderm
|
|
gptkbp:percentageOfLiverCells
|
70-85%
|
|
gptkbp:regenerates
|
high capacity
|
|
gptkbp:secretes
|
albumin
clotting factors
complement proteins
|
|
gptkbp:shape
|
polygonal
|
|
gptkbp:surfaceMarkers
|
gptkb:ASGPR
gptkb:CYP_enzymes
albumin
|
|
gptkbp:bfsParent
|
gptkb:Cytochrome_P450_3A4
gptkb:SLC10A1
gptkb:human_induced_pluripotent_stem_cells
gptkb:CYP3A4
gptkb:interleukin-6
gptkb:CD81
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
hepatocytes
|