Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
Cell
|
gptkbp:cytoplasmContains |
lysosomes
|
gptkbp:dysregulationAssociatedWith |
gptkb:osteopetrosis
|
gptkbp:firstDescribed |
Albert Kölliker
|
gptkbp:function |
bone resorption
|
https://www.w3.org/2000/01/rdf-schema#label |
osteoclasts
|
gptkbp:inhibitedBy |
gptkb:calcitonin
osteoprotegerin |
gptkbp:location |
bone tissue
|
gptkbp:marking |
TRAP (tartrate-resistant acid phosphatase)
cathepsin K |
gptkbp:multinucleated |
true
|
gptkbp:origin |
monocyte-macrophage lineage
|
gptkbp:overactivityAssociatedWith |
gptkb:bone
|
gptkbp:promotion |
gptkb:RANKL
M-CSF |
gptkbp:role |
bone remodeling
calcium homeostasis |
gptkbp:secretes |
hydrochloric acid
proteolytic enzymes |
gptkbp:surface |
ruffled border
|
gptkbp:bfsParent |
gptkb:Calcitonin_receptor
|
gptkbp:bfsLayer |
6
|