osteoclasts

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf Cell
gptkbp:cytoplasmContains lysosomes
gptkbp:dysregulationAssociatedWith gptkb:osteopetrosis
gptkbp:firstDescribed Albert Kölliker
gptkbp:function bone resorption
https://www.w3.org/2000/01/rdf-schema#label osteoclasts
gptkbp:inhibitedBy gptkb:calcitonin
osteoprotegerin
gptkbp:location bone tissue
gptkbp:marking TRAP (tartrate-resistant acid phosphatase)
cathepsin K
gptkbp:multinucleated true
gptkbp:origin monocyte-macrophage lineage
gptkbp:overactivityAssociatedWith gptkb:bone
gptkbp:promotion gptkb:RANKL
M-CSF
gptkbp:role bone remodeling
calcium homeostasis
gptkbp:secretes hydrochloric acid
proteolytic enzymes
gptkbp:surface ruffled border
gptkbp:bfsParent gptkb:Calcitonin_receptor
gptkbp:bfsLayer 6