Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Cell
|
| gptkbp:cytoplasmContains |
lysosomes
|
| gptkbp:dysregulationAssociatedWith |
gptkb:osteopetrosis
|
| gptkbp:firstDescribed |
Albert Kölliker
|
| gptkbp:function |
bone resorption
|
| gptkbp:inhibitedBy |
gptkb:calcitonin
osteoprotegerin |
| gptkbp:location |
bone tissue
|
| gptkbp:marking |
TRAP (tartrate-resistant acid phosphatase)
cathepsin K |
| gptkbp:multinucleated |
true
|
| gptkbp:origin |
monocyte-macrophage lineage
|
| gptkbp:overactivityAssociatedWith |
gptkb:bone
|
| gptkbp:promotion |
gptkb:RANKL
M-CSF |
| gptkbp:role |
bone remodeling
calcium homeostasis |
| gptkbp:secretes |
hydrochloric acid
proteolytic enzymes |
| gptkbp:surface |
ruffled border
|
| gptkbp:bfsParent |
gptkb:Carbonic_anhydrase_II
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
osteoclasts
|