Hematopoietic progenitor cell antigen CD34
GPTKB entity
Statements (56)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:CD34_antigen
gptkb:Cluster_of_Differentiation_34 gp105-120 CD34 molecule HPCA1 Hematopoietic progenitor cell antigen Mucosialin |
| gptkbp:antibodyTarget |
gptkb:Class_I
gptkb:Class_II gptkb:Class_III 581 4H11 8G12 My10 QBEnd/10 TUK3 |
| gptkbp:cellSurfaceMarker |
hematopoietic stem cells
vascular endothelial cells endothelial progenitor cells |
| gptkbp:discoveredBy |
1984
|
| gptkbp:encodedBy |
gptkb:CD34_gene
|
| gptkbp:expressedIn |
bone marrow
fibroblasts peripheral blood mesenchymal stem cells umbilical cord blood some tumor cells early lymphoid progenitors interstitial dendritic cells |
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
signal transduction
cell adhesion regulation of hematopoietic cell differentiation |
| gptkbp:gene |
gptkb:CD34
|
| gptkbp:glycosylation |
heavily glycosylated
|
| gptkbp:HGNC_ID |
HGNC:1663
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hematopoietic progenitor cell antigen CD34
|
| gptkbp:locatedOnChromosome |
1q32.2
|
| gptkbp:molecularWeight |
110 kDa
|
| gptkbp:OMIM |
142230
|
| gptkbp:structure |
single-pass type I membrane protein
|
| gptkbp:UniProtID |
P28906
|
| gptkbp:used_as_marker_for |
angiogenesis
hematopoietic stem cell transplantation tumor vasculature |
| gptkbp:used_in |
flow cytometry
stem cell isolation |
| gptkbp:used_in_diagnosis_of |
leukemia
myelodysplastic syndromes lymphomas soft tissue tumors vascular tumors |
| gptkbp:bfsParent |
gptkb:CD34
|
| gptkbp:bfsLayer |
8
|