Stem Cell Factor

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:protein
cytokine
gptkbp:alsoKnownAs gptkb:SCF
gptkb:KIT_ligand
gptkb:steel_factor
gptkbp:binds gptkb:c-Kit_receptor
gptkbp:category growth factor
hematopoietic growth factor
paracrine signaling molecule
gptkbp:discoveredIn gptkb:mouse
gptkbp:encodedBy gptkb:KITLG_gene
gptkbp:Entrez_Gene_ID 4254
gptkbp:existsIn membrane-bound form
soluble form
gptkbp:function gametogenesis regulation
hematopoiesis regulation
melanogenesis regulation
https://www.w3.org/2000/01/rdf-schema#label Stem Cell Factor
gptkbp:involvedIn cell proliferation
cell survival
cell migration
cell signaling
gptkbp:locatedOnChromosome gptkb:chromosome_12_(human)
gptkbp:medicalUse bone marrow transplantation
stem cell mobilization
gptkbp:molecularWeight ~30 kDa
gptkbp:mutationAssociatedWith gptkb:anemia
infertility
pigmentation defects
gptkbp:OMIM 184745
gptkbp:producedBy endothelial cells
fibroblasts
stromal cells
gptkbp:recipient gptkb:receptor_tyrosine_kinase
gptkb:CD117
gptkbp:role germ cell development
stem cell maintenance
allergic response
pigmentation
mast cell development
gptkbp:species gptkb:human
gptkb:mouse
right
gptkbp:structure gptkb:protein
gptkbp:UniProtID P21583
gptkbp:usedIn stem cell culture
hematopoietic stem cell expansion
gptkbp:bfsParent gptkb:SCF
gptkbp:bfsLayer 6