|
gptkbp:instance_of
|
gptkb:protein
|
|
gptkbp:associated_with
|
gptkb:chronic_myeloid_leukemia
gptkb:gastrointestinal_stromal_tumors
gptkb:Oncology
gptkb:stem_cell_factor
mast cell development
|
|
gptkbp:breeding_range
|
chromosome 4
|
|
gptkbp:clinical_trial
|
target for cancer therapy
biomarker for certain cancers
role in cell survival
role in differentiation
role in tumorigenesis
|
|
gptkbp:diseases
|
gptkb:chronic_myeloid_leukemia
gptkb:gastrointestinal_stromal_tumors
gptkb:Oncology
gptkb:alopecia_areata
deafness
hypopigmentation
mastocytosis
piebaldism
|
|
gptkbp:function
|
gptkb:receptor_tyrosine_kinase
|
|
gptkbp:genetic_studies
|
impaired cell growth
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
c-Kit
|
|
gptkbp:initiated_by
|
gptkb:imatinib
gptkb:sunitinib
gptkb:regorafenib
|
|
gptkbp:involved_in
|
cell signaling
|
|
gptkbp:is_expressed_in
|
gptkb:hematopoietic_stem_cells
germ cells
melanocytes
|
|
gptkbp:pathway
|
MAPK pathway
JAK/ STAT pathway
PI3 K/ AKT pathway
|
|
gptkbp:promoter
|
KIT
|
|
gptkbp:role
|
hematopoiesis
|
|
gptkbp:type
|
gptkb:Biology
membrane protein
growth factor receptor
|
|
gptkbp:bfsParent
|
gptkb:interstitial_cells_of_Cajal
|
|
gptkbp:bfsLayer
|
7
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