Statements (42)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:bfsLayer |
2
|
| gptkbp:bfsParent |
gptkb:physicist
|
| gptkbp:antagonist |
binds to Trk B receptor
binds to p75 NTR receptor |
| gptkbp:associated_with |
gptkb:Magic:_The_Gathering_set
gptkb:learning neuroplasticity |
| gptkbp:form |
exists in multiple isoforms
|
| gptkbp:full_name |
gptkb:physicist
|
| gptkbp:function |
encourages the growth of new neurons and synapses
supports the survival of existing neurons |
| https://www.w3.org/2000/01/rdf-schema#label |
BDNF
|
| gptkbp:influences |
mood regulation
cognitive function |
| gptkbp:is_represented_in |
increased in response to neuronal activity
|
| gptkbp:location |
found in the brain and spinal cord
|
| gptkbp:promoter |
gptkb:BDNF_gene
|
| gptkbp:regulatory_compliance |
regulated by stress
regulated by diet regulated by physical exercise regulated by sleep |
| gptkbp:research |
studied in the context of cognitive decline
studied in the context of neurodevelopment studied in the context of neurogenesis studied in the context of neuroprotection studied in the context of psychiatric disorders |
| gptkbp:research_areas |
potential therapeutic target for enhancing cognitive function
potential biomarker for mental health disorders potential role in enhancing learning and memory potential role in recovery from brain injuries potential role in treating neurodegenerative diseases |
| gptkbp:role |
plays a role in long-term depression
plays a role in long-term potentiation plays a role in synaptic plasticity |
| gptkbp:social_responsibility |
linked to Alzheimer's disease
linked to Huntington's disease linked to autism spectrum disorders linked to depression linked to schizophrenia |
| gptkbp:treatment |
target for antidepressant therapies
potential target for neurodegenerative disease therapies |