|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:Beta-NGF
gptkb:NGFB
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
neurodegenerative diseases
pain modulation
|
|
gptkbp:category
|
growth factor
neurotrophin
|
|
gptkbp:discoveredBy
|
gptkb:Rita_Levi-Montalcini
gptkb:Stanley_Cohen
|
|
gptkbp:discoveredIn
|
1950s
|
|
gptkbp:encodedBy
|
NGF gene
|
|
gptkbp:Entrez_Gene_ID
|
4803
|
|
gptkbp:expressedIn
|
central nervous system
peripheral nervous system
|
|
gptkbp:fullName
|
gptkb:Nerve_Growth_Factor
|
|
gptkbp:function
|
promotes survival and growth of neurons
regulates development of sympathetic and sensory neurons
|
|
gptkbp:gene
|
gptkb:NGF
|
|
gptkbp:HGNC_ID
|
7808
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NGF
|
|
gptkbp:inhibitedBy
|
neuronal cell death
|
|
gptkbp:locatedOnChromosome
|
gptkb:1p13.1
|
|
gptkbp:molecularWeight
|
26 kDa (mature form)
|
|
gptkbp:mutationAssociatedWith
|
gptkb:hereditary_sensory_and_autonomic_neuropathy_type_IV
gptkb:hereditary_sensory_and_autonomic_neuropathy_type_V
|
|
gptkbp:OMIM
|
162030
|
|
gptkbp:organism
|
gptkb:human
gptkb:mouse
right
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
gptkb:1BET
|
|
gptkbp:promotion
|
gptkb:synaptic_plasticity
axon growth
dendrite growth
|
|
gptkbp:recipient
|
gptkb:TrkA
gptkb:p75NTR
|
|
gptkbp:regulates
|
inflammation
immune response
apoptosis in neurons
neurite outgrowth
|
|
gptkbp:relatedTo
|
gptkb:BDNF
gptkb:NT-3
gptkb:NT-4/5
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:UniProtID
|
gptkb:P01138
|
|
gptkbp:usedIn
|
pain therapy research
research on nerve regeneration
|
|
gptkbp:bfsParent
|
gptkb:nerve_growth_factor
gptkb:Marine_Corps_Base_Hawaii
|
|
gptkbp:bfsLayer
|
5
|