Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
neurodegenerative diseases
psychiatric disorders depression (when levels are low) |
| gptkbp:binds |
gptkb:TrkB_receptor
gptkb:p75NTR_receptor |
| gptkbp:cleavage |
gptkb:proBDNF
|
| gptkbp:derivedFrom |
gptkb:proBDNF
|
| gptkbp:encodedBy |
gptkb:BDNF_gene
|
| gptkbp:fullName |
gptkb:mature_brain-derived_neurotrophic_factor
|
| gptkbp:function |
promotes neuronal survival
stimulates neurogenesis supports synaptic plasticity |
| https://www.w3.org/2000/01/rdf-schema#label |
mature BDNF
|
| gptkbp:location |
central nervous system
peripheral nervous system |
| gptkbp:molecularWeight |
~14 kDa
|
| gptkbp:regulates |
stress
physical activity neuronal activity antidepressants |
| gptkbp:role |
gptkb:long-term_potentiation
synaptic transmission axon growth neuronal differentiation learning and memory dendritic growth |
| gptkbp:sequence |
polypeptide
|
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:bfsParent |
gptkb:BDNF
|
| gptkbp:bfsLayer |
7
|